Economically designed for the single-use market, Bio-Simplex® Sampling Manifold systems reduce the risk of cross-contamination while delivering significant additional time and cost savings in the areas of assembly, cleaning, and cleaning validation. They are available in four-, six-, eight- and ten-bottle configurations, with a 500-mL effluent bottle at the end of the manifold. Each individual 60-mL sampling bottle is connected to the manifold with 10 inches of tubing and a Pure-Fit® TC clamp, and features an EZ Top® container closure, a 0.2 μM vent filter (for sterile gas exchange) and a polyethylene cap. All EZ Top closures, the tubing and the manifold itself are made from animal derived component free (ADCF) C-Flex® pharmaceutical-grade thermoplastic elastomer (TPE) resin. The entire system is engineered to ensure an unobstructed fluid path, extremely low levels of extractables and a secure elastomeric seal between closure and bottle. Bio-Simplex manifolds are easily used with sterile connecting devices and thermal tubing sealers, and come with a carrying tray that holds up to ten sampling bottles and the larger purge bottle. For unique applications that require modification or customization, contact our customer service department.